BDBM8274 3-(2-chlorophenyl)-4-{[4-(methylsulfanyl)phenyl]amino}-2,5-dihydro-1H-pyrrole-2,5-dione::4-arylmaleimide deriv. 6ee

SMILES CSc1ccc(NC2=C(C(=O)NC2=O)c2ccccc2Cl)cc1

InChI Key InChIKey=XMKRZXOTGFXMPH-UHFFFAOYSA-N

Data  2 KI  2 IC50  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8274   

TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
University Of Campinas (Unicamp)

Curated by ChEMBL
LigandPNGBDBM8274(3-(2-chlorophenyl)-4-{[4-(methylsulfanyl)phenyl]am...)
Affinity DataKd:  580nMAssay Description:Inhibition of wild-type human full length GSK3A (M1 to S483 residues) expressed in bacterial expression system by Kinomescan method relative to contr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
University Of Campinas (Unicamp)

Curated by ChEMBL
LigandPNGBDBM8274(3-(2-chlorophenyl)-4-{[4-(methylsulfanyl)phenyl]am...)
Affinity DataIC50:  161nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed