BDBM8274 3-(2-chlorophenyl)-4-{[4-(methylsulfanyl)phenyl]amino}-2,5-dihydro-1H-pyrrole-2,5-dione::4-arylmaleimide deriv. 6ee
SMILES CSc1ccc(NC2=C(C(=O)NC2=O)c2ccccc2Cl)cc1
InChI Key InChIKey=XMKRZXOTGFXMPH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 8274
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
University Of Campinas (Unicamp)
Curated by ChEMBL
University Of Campinas (Unicamp)
Curated by ChEMBL
Affinity DataKd: 580nMAssay Description:Inhibition of wild-type human full length GSK3A (M1 to S483 residues) expressed in bacterial expression system by Kinomescan method relative to contr...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
University Of Campinas (Unicamp)
Curated by ChEMBL
University Of Campinas (Unicamp)
Curated by ChEMBL
Affinity DataIC50: 161nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair